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Human IGF1R HEK293 Cell Lysate

For research use only. Not intended for any clinical use.

Cat. No. :   CLOE-1679 Host Cell :   HEK293

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Cell Lysate Information

Gene Information

Cat. No. CLOE-1679
Introduction This cell lysate over-expresses the extracellular domain of human IGF1R (NP_000866.1) (Met 1-Asn 932) fused with a polyhistidine tag at the C-terminus. Purification of target protein (s) from this cell lysate has been verified.
Target Gene IGF1R
Host Cell HEK293
Host Cell Species Homo sapiens (Human)
Applications Positive control for Western Blot (WB), antibody verification, protein purification
Growth Properties Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO2. Split at 80-90% confluence, approximately 1:3-1:6.
Media Type Cells were cultured in DMEM supplemented with 10% fetal bovine serum.
Freeze Medium Complete medium supplemented with 10% (v/v) DMSO
Storage Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping Ice package
Gene Name IGF1R insulin-like growth factor 1 receptor [ Homo sapiens ]
Gene Symbol IGF1R
Synonyms IGFR; CD221; IGFIR; JTK13
Gene Description insulin-like growth factor 1 receptor
GeneID 3480
Uni ProtID P08069
mRNA Refseq NM_000875.3
Protein Refseq NP_000866.1
Chromosome Location 15q26.3
Function ATP binding; identical protein binding; insulin binding; insulin receptor binding; insulin receptor substrate binding; insulin-like growth factor I binding; insulin-like growth factor binding; insulin-like growth factor-activated receptor activity; phosphatidylinositol 3-kinase binding; protein binding; protein tyrosine kinase activity;
Pathway Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Apoptosis, organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Focal Adhesion, organism-specific biosystem;
MIM 147370
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