Panoply™ Human IGF1R Knockdown Stable Cell Line

Name: Panoply™ Human IGF1R Knockdown Stable Cell Line
SKU: CSC-DC007477
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC007477

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC007477
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	IGF1R
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	IGF1R insulin-like growth factor 1 receptor [ Homo sapiens ]
Gene Symbol	IGF1R
Synonyms	IGFR; CD221; IGFIR; JTK13
Gene Description	insulin-like growth factor 1 receptor
GeneID	3480
Uni ProtID	P08069
mRNA Refseq	NM_000875.3
Protein Refseq	NP_000866.1
Chromosome Location	15q26.3
Function	ATP binding; identical protein binding; insulin binding; insulin receptor binding; insulin receptor substrate binding; insulin-like growth factor I binding; insulin-like growth factor binding; insulin-like growth factor-activated receptor activity; phosphatidylinositol 3-kinase binding; protein binding; protein tyrosine kinase activity;
Pathway	Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Apoptosis, organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Focal Adhesion, organism-specific biosystem;
MIM	147370

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