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Human GCLC ORF clone (NM_001197115.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCL111025

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Product Information

Gene Information

Cat. No. CDCL111025
Description Homo sapiens glutamate-cysteine ligase, catalytic subunit (GCLC), transcript variant 2, mRNA.
Product Type ORF clone
Gene Abbr GCLC
Gene Name GCLC glutamate-cysteine ligase, catalytic subunit [ Homo sapiens ]
Species Human
ORF Size 1800bp
Format purified plasmid
Vector pDONR
Warning Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.
Gene Name GCLC glutamate-cysteine ligase, catalytic subunit [ Homo sapiens ]
Gene Symbol GCLC
Synonyms GCLC; glutamate-cysteine ligase, catalytic subunit; GLCL, GLCLC; glutamate--cysteine ligase catalytic subunit; GCS; gamma-ECS; GCS heavy chain; gamma-glutamylcysteine synthetase; GCL; GLCL; GLCLC;
GeneID 2729
Uni ProtID P48506
mRNA Refseq BC022487
Chromosome Location 6p12
Function ADP binding; ATP binding; coenzyme binding; glutamate binding; glutamate-cysteine ligase activity; glutamate-cysteine ligase activity; ligase activity; magnesium ion binding; nucleotide binding; protein heterodimerization activity;
Pathway Biological oxidations, organism-specific biosystem; Glutathione biosynthesis, glutamate => glutathione, organism-specific biosystem; Glutathione biosynthesis, glutamate => glutathione, conserved biosystem; Glutathione conjugation, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem;
MIM 606857
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