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Panoply™ Human GCLC Knockdown Stable Cell Line

Cat.No.
CSC-DC006165
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
GCLC
Synonyms
GCLC; glutamate-cysteine ligase, catalytic subunit; GLCL, GLCLC; glutamate--cysteine ligase catalytic subunit; GCS; gamma-ECS; GCS heavy chain; gamma-glutamylcysteine synthetase; GCL; GLCL; GLCLC;
Gene ID
UniProt ID
P48506
mRNA Refseq
BC022487
Chromosome Location
6p12
Function
ADP binding; ATP binding; coenzyme binding; glutamate binding; glutamate-cysteine ligase activity; glutamate-cysteine ligase activity; ligase activity; magnesium ion binding; nucleotide binding; protein heterodimerization activity;
Pathway
Biological oxidations, organism-specific biosystem; Glutathione biosynthesis, glutamate => glutathione, organism-specific biosystem; Glutathione biosynthesis, glutamate => glutathione, conserved biosystem; Glutathione conjugation, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem;
MIM

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