Human ACVR2B(His) HEK293 Cell Lysate

Name: Human ACVR2B(His) HEK293 Cell Lysate
SKU: CLOE-1594
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CLOE-1594 Host Cell : HEK293

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Cell Lysate Information

Gene Information

Cat. No.	CLOE-1594
Introduction	This cell lysate over-expresses the extracellular domain of human ACVR2B (NP_001097.2) (Met 1-Thr 134) fused with a polyhistidine tag at the C-terminus. Purification of target protein (s) from this cell lysate has been verified.
Target Gene	ACVR2B
Host Cell	HEK293
Host Cell Species	Homo sapiens (Human)
Applications	Positive control for Western Blot (WB), antibody verification, protein purification
Growth Properties	Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO₂. Split at 80-90% confluence, approximately 1:3-1:6.
Media Type	Cells were cultured in DMEM supplemented with 10% fetal bovine serum.
Freeze Medium	Complete medium supplemented with 10% (v/v) DMSO
Storage	Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping	Ice package

Gene Name	ACVR2B activin A receptor, type IIB [ Homo sapiens ]
Gene Symbol	ACVR2B
Synonyms	HTX4; ACTRIIB; ActR-IIB
Gene Description	activin A receptor, type IIB
Gene ID	93
Uni Prot ID	Q13705
m RNA Refseq	NM_001106.3
Protein Refseq	NP_001097.2
Chromosome Location	3p22
Function	ATP binding; activin binding; contributes_to activin receptor activity, type II; growth factor binding; metal ion binding; protein binding; protein serine/threonine kinase activity; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; receptor signaling protein serine/threonine kinase activity; transforming growth factor beta-activated receptor activity;
Pathway	Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Developmental Biology, organism-specific biosystem; Regulation of Signaling by NODAL, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by BMP, organism-specific biosystem; Signaling by NODAL, organism-specific biosystem;
MIM	602730

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