shRNA set against Rat Apex1(NM_024148.1)

Name: shRNA set against Rat Apex1(NM_024148.1)
SKU: SHG064459
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHG064459

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Product Information

Gene Information

Cat. No.	SHG064459
Description	Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence. The sequences of 19~29mer shRNAi will be delivered with shRNA clones.
Gene Abbr	Apex1
Gene Name	Apex1 APEX nuclease (multifunctional DNA repair enzyme) 1 [ Rattus norvegicus ]
Species	Rat
Report Gene	eGFP
Content	Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence.
Promoter	H1
Selection	Puromycin
Format	5 μg purified plasmid
Unit Size	5 μg
Sequence	The sequences of 19~29mer shRNAi will be delivered with shRNA clones.
Shipping	Typically ships in 2-3 weeks

Gene Name	Apex1 APEX nuclease (multifunctional DNA repair enzyme) 1 [ Rattus norvegicus ]
Gene Symbol	Apex1
Synonyms	APE; Apex; REF-1
Gene Description	apurinic/apyrimidinic endonuclease 1
Gene ID	79116
Uni Prot ID	P43138
m RNA Refseq	NM_024148.1
Protein Refseq	NP_077062.1
Chromosome Location	15p14
Function	3-5 exonuclease activity; 3-5 exonuclease activity; DNA binding; DNA binding; DNA-(apurinic or apyrimidinic site) lyase activity; DNA-(apurinic or apyrimidinic site) lyase activity; NF-kappaB binding; RNA binding; chromatin DNA binding; chromatin DNA binding; damaged DNA binding; damaged DNA binding; endonuclease activity; endoribonuclease activity; metal ion binding; metal ion binding; oxidoreductase activity; oxidoreductase activity; phosphoric diester hydrolase activity; protein binding; protein complex binding; site-specific endodeoxyribonuclease activity, specific for altered base; site-specific endodeoxyribonuclease activity, specific for altered base; transcription coactivator activity; transcription coactivator activity;
Pathway	BER complex, organism-specific biosystem; BER complex, conserved biosystem; Base Excision Repair, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Base-free sugar-phosphate removal via the single-nucleotide replacement pathway, organism-specific biosystem; DNA Repair, organism-specific biosystem;

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