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shRNA set against Mouse TIMP1 (NM_011593.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH427524

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Gene Information

Cat. No. SHH427524
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr TIMP1
Gene Name Timp1 tissue inhibitor of metalloproteinase 1 [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Timp1 tissue inhibitor of metalloproteinase 1 [ Mus musculus ]
Gene Symbol Timp1
Synonyms Clgi; Timp; TIMP-1
Gene Description tissue inhibitor of metalloproteinase 1
GeneID 21857
Uni ProtID B1AUP1
mRNA Refseq NM_011593.2
Protein Refseq NP_035723.2
Chromosome Location X A1.3; X 6.2 cM
Function enzyme inhibitor activity; metal ion binding; metalloendopeptidase inhibitor activity;
Pathway Activation of Matrix Metalloproteinases, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Extracellular matrix organization, organism-specific biosystem; HIF-1 signaling pathway, organism-specific biosystem; Hemostasis, organism-specific biosystem; Matrix Metalloproteinases, organism-specific biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem;
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