Rat TIMP1 ORF clone(NM_053819.1)

Name: Rat TIMP1 ORF clone(NM_053819.1)
SKU: CDCL186458
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL186458

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Product Information

Gene Information

Cat. No.	CDCL186458
Description	ORF Clone of Rattus norvegicus TIMP metallopeptidase inhibitor 1 DNA.
Product Type	ORF clone
Gene Abbr	TIMP1
Species	Rat
ORF Size	654bp
Vector	pMD18-T
Warning	This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage	store at -20°C

Target Gene

TIMP1

Background

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]

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