shRNA set against Mouse SQSTM1 (NM_011018.2)

Name: shRNA set against Mouse SQSTM1 (NM_011018.2)
SKU: SHH417616
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH417616

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Product Information

Gene Information

Cat. No.	SHH417616
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	SQSTM1
Gene Name	Sqstm1 sequestosome 1 [ Mus musculus ]
Species	Mouse
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	Sqstm1 sequestosome 1 [ Mus musculus ]
Gene Symbol	Sqstm1
Synonyms	Osi; p62; A170; STAP; OSF-6
Gene Description	sequestosome 1
GeneID	18412
Uni ProtID	Q64337
mRNA Refseq	NM_011018.2
Protein Refseq	NP_035148.1
Chromosome Location	11; 11 B1.2
Function	K63-linked polyubiquitin binding; SH2 domain binding; identical protein binding; identical protein binding; metal ion binding; protein binding; protein homodimerization activity; protein kinase C binding; protein kinase binding; transcription cofactor activity; ubiquitin binding; zinc ion binding;
Pathway	Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; IL-1 Signaling Pathway, organism-specific biosystem; Immune System, organism-specific biosystem; Interleukin-1 signaling, organism-specific biosystem; NF-kB is activated and signals survival, organism-specific biosystem; NRIF signals cell death from the nucleus, organism-specific biosystem;

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