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shRNA set against Mouse MCL1 (NM_008562.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH339255

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Gene Information

Cat. No. SHH339255
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr MCL1
Gene Name Mcl1 myeloid cell leukemia sequence 1 [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Mcl1 myeloid cell leukemia sequence 1 [ Mus musculus ]
Gene Symbol Mcl1
Synonyms Mcl-1; AW556805
Gene Description myeloid cell leukemia sequence 1
Gene ID 17210
Uni Prot ID P97287
m RNA Refseq NM_008562.3
Protein Refseq NP_032588.1
Chromosome Location 3 F2.1; 3 43.6 cM
Function BH domain binding; BH3 domain binding; BH3 domain binding; protein binding; protein dimerization activity; protein heterodimerization activity;
Pathway Apoptosis, organism-specific biosystem; IL-7 Signaling Pathway, organism-specific biosystem; PI3K-Akt signaling pathway, organism-specific biosystem; PI3K-Akt signaling pathway, conserved biosystem;
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