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Panoply™ Human MCL1 Knockdown Stable Cell Line

Cat.No.
CSC-DC009311
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
MCL1
Synonyms
MCL1; myeloid cell leukemia sequence 1 (BCL2-related); induced myeloid leukemia cell differentiation protein Mcl-1; BCL2L3; Mcl 1; bcl-2-like protein 3; myeloid cell leukemia ES; bcl-2-related protein EAT/mcl1; TM; EAT; MCL1L; MCL1S; Mcl-1; MCL1-ES; bcl2-L-3; mcl1/EAT; MGC1839; MGC104264;
Gene ID
UniProt ID
Q07820
mRNA Refseq
BC017197
Chromosome Location
1q21
Function
BH3 domain binding; protein binding; protein channel activity; protein heterodimerization activity;
Pathway
Apoptosis, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; E2F transcription factor network, organism-specific biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem; IL-7 Signaling Pathway, organism-specific biosystem; IL6-mediated signaling events, organism-specific biosystem;
MIM

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