shRNA set against Human MCL1 (NM_021960.4)

Name: shRNA set against Human MCL1 (NM_021960.4)
SKU: SHH339251
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH339251

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Product Information

Gene Information

Cat. No.	SHH339251
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	MCL1
Gene Name	MCL1 myeloid cell leukemia sequence 1 (BCL2-related) [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	MCL1 myeloid cell leukemia sequence 1 (BCL2-related) [ Homo sapiens ]
Gene Symbol	MCL1
Synonyms	MCL1; myeloid cell leukemia sequence 1 (BCL2-related); induced myeloid leukemia cell differentiation protein Mcl-1; BCL2L3; Mcl 1; bcl-2-like protein 3; myeloid cell leukemia ES; bcl-2-related protein EAT/mcl1; TM; EAT; MCL1L; MCL1S; Mcl-1; MCL1-ES; bcl2-L-3; mcl1/EAT; MGC1839; MGC104264;
Gene ID	4170
Uni Prot ID	Q07820
m RNA Refseq	BC017197
Chromosome Location	1q21
Function	BH3 domain binding; protein binding; protein channel activity; protein heterodimerization activity;
Pathway	Apoptosis, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; E2F transcription factor network, organism-specific biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem; IL-7 Signaling Pathway, organism-specific biosystem; IL6-mediated signaling events, organism-specific biosystem;
MIM	159552

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