shRNA set against Mouse CDKN2A (NM_009877.2)

Name: shRNA set against Mouse CDKN2A (NM_009877.2)
SKU: SHH260849
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH260849

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Product Information

Gene Information

Cat. No.	SHH260849
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	CDKN2A
Gene Name	Cdkn2a cyclin-dependent kinase inhibitor 2A [ Mus musculus ]
Species	Mouse
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	Cdkn2a cyclin-dependent kinase inhibitor 2A [ Mus musculus ]
Gene Symbol	Cdkn2a
Synonyms	Arf; p16; MTS1; Pctr1; p19ARF; p16INK4a; p19; ARF-INK4a; INK4a-ARF; Ink4a/Arf; p16(INK4a)
Gene Description	cyclin-dependent kinase inhibitor 2A
Gene ID	12578
Uni Prot ID	P51480
m RNA Refseq	NM_001040654.1
Protein Refseq	NP_001035744.1
Chromosome Location	4 C3-C6; 4 42.7 cM
Function	DNA binding; MDM2/MDM4 family protein binding; NF-kappaB binding; cyclin-dependent protein kinase inhibitor activity; cyclin-dependent protein kinase inhibitor activity; p53 binding; protein binding; protein kinase binding; sequence-specific DNA binding transcription factor activity; transcription factor binding; ubiquitin-protein ligase inhibitor activity;
Pathway	Apoptosis, organism-specific biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem;

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