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shRNA set against Human CDKN2A (NM_000077.4)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH260845

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Gene Information

Cat. No. SHH260845
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr CDKN2A
Gene Name CDKN2A cyclin-dependent kinase inhibitor 2A [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name CDKN2A cyclin-dependent kinase inhibitor 2A [ Homo sapiens ]
Gene Symbol CDKN2A
Synonyms ARF; MLM; P14; P16; P19; CMM2; INK4; MTS1; TP16; CDK4I; CDKN2; INK4A; MTS-1; P14ARF; P19ARF; P16INK4; P16INK4A; P16-INK4A
Gene ID 1029
Uni Prot ID P42771
m RNA Refseq NM_000077.4
Protein Refseq NP_000068.1
Chromosome Location 9p21
Function DNA binding; MDM2/MDM4 family protein binding; NF-kappaB binding; cyclin-dependent protein kinase inhibitor activity; p53 binding; protein binding; protein kinase binding; sequence-specific DNA binding transcription factor activity; transcription factor binding; ubiquitin-protein ligase inhibitor activity;
Pathway Apoptosis, organism-specific biosystem; Apoptosis Modulation and Signaling, organism-specific biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem;
MIM 600160
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