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Panoply™ Human CDKN2A Knockdown Stable Cell Line

Cat.No.
CSC-DC002892
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
CDKN2A
Synonyms
ARF; MLM; P14; P16; P19; CMM2; INK4; MTS1; TP16; CDK4I; CDKN2; INK4A; MTS-1; P14ARF; P19ARF; P16INK4; P16INK4A; P16-INK4A
Gene ID
UniProt ID
P42771
mRNA Refseq
Protein Refseq
Chromosome Location
9p21
Function
DNA binding; MDM2/MDM4 family protein binding; NF-kappaB binding; cyclin-dependent protein kinase inhibitor activity; p53 binding; protein binding; protein kinase binding; sequence-specific DNA binding transcription factor activity; transcription factor binding; ubiquitin-protein ligase inhibitor activity;
Pathway
Apoptosis, organism-specific biosystem; Apoptosis Modulation and Signaling, organism-specific biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem;
MIM

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