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shRNA set against Mouse CCL5 (NM_013653.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH257701

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Gene Information

Cat. No. SHH257701
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr CCL5
Gene Name Ccl5 chemokine (C-C motif) ligand 5 [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Ccl5 chemokine (C-C motif) ligand 5 [ Mus musculus ]
Gene Symbol Ccl5
Synonyms SISd; Scya5; RANTES; TCP228; MuRantes
Gene Description chemokine (C-C motif) ligand 5
GeneID 20304
Uni ProtID P30882
mRNA Refseq NM_013653.3
Protein Refseq NP_038681.2
Chromosome Location 11 C; 11 47.4 cM
Function CCR1 chemokine receptor binding; CCR1 chemokine receptor binding; CCR5 chemokine receptor binding; chemoattractant activity; chemokine activity; chemokine receptor antagonist activity; chemokine receptor binding; cytokine activity; heparin binding; phosphatidylinositol phospholipase C activity; phospholipase activator activity; protein homodimerization activity; protein kinase activity; protein self-association; receptor signaling protein tyrosine kinase activator activity;
Pathway Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem;
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