shRNA set against Mouse BRCA1 (NM_009764.3)

Name: shRNA set against Mouse BRCA1 (NM_009764.3)
SKU: SHH247550
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH247550

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Product Information

Gene Information

Cat. No.	SHH247550
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	BRCA1
Gene Name	Brca1 breast cancer 1 [ Mus musculus ]
Species	Mouse
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	Brca1 breast cancer 1 [ Mus musculus ]
Gene Symbol	BRCA1
GeneID	12189
Uni ProtID	P48754
mRNA Refseq	NM_009764.3
Protein Refseq	NP_033894.3
Chromosome Location	11 D; 11 60.5 cM
Function	DNA binding; RNA binding; damaged DNA binding; enzyme binding; ligase activity; metal ion binding; transcription regulatory region DNA binding; transcription regulatory region DNA binding; ubiquitin protein ligase binding; ubiquitin-protein ligase activity; zinc ion binding;
Pathway	ATM mediated phosphorylation of repair proteins, organism-specific biosystem; ATM mediated response to DNA double-strand break, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem; Cell Cycle, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; DNA Repair, organism-specific biosystem; Double-Strand Break Repair, organism-specific biosystem; Fanconi Anemia pathway, organism-specific biosystem; Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem; Homologous Recombination Repair, organism-specific biosystem; Homologous recombination repair of replication-independent double-strand breaks, organism-specific biosystem; Meiosis, organism-specific biosystem; Meiotic Recombination, organism-specific biosystem; Meiotic Synapsis, organism-specific biosystem; PI3K-Akt signaling pathway, organism-specific biosystem; PI3K-Akt signaling pathway, conserved biosystem; PluriNetWork, organism-specific biosystem; Recruitment of repair and signaling proteins to double-strand breaks, organism-specific biosystem; Ubiquitin mediated proteolysis, organism-specific biosystem; Ubiquitin mediated proteolysis, conserved biosystem; estrogen signalling, organism-specific biosystem; mRNA processing, organism-specific biosystem;

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