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shRNA set against Mouse BAD (NM_007522.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH244610

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Gene Information

Cat. No. SHH244610
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr BAD
Gene Name Bad BCL2-associated agonist of cell death [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Bad BCL2-associated agonist of cell death [ Mus musculus ]
Gene Symbol Bad
Synonyms Bbc2; AI325008
Gene Description Bcl-associated death promoter
GeneID 12015
Uni ProtID Q61337
mRNA Refseq NM_007522.2
Protein Refseq NP_031548.1
Chromosome Location 19 A; 19
Function cysteine-type endopeptidase activator activity involved in apoptotic process; cysteine-type endopeptidase activator activity involved in apoptotic process; lipid binding; phospholipid binding; protein binding; protein heterodimerization activity; protein kinase B binding; protein kinase binding; protein phosphatase 2B binding; protein phosphatase binding;
Pathway AKT phosphorylates targets in the cytosol, organism-specific biosystem; Activation of BAD and translocation to mitochondria, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adaptive Immune System, organism-specific biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem;
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