shRNA set against Human UPF1 (NM_002911.3)

Name: shRNA set against Human UPF1 (NM_002911.3)
SKU: SHH440733
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH440733

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Product Information

Gene Information

Cat. No.	SHH440733
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	UPF1
Gene Name	UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) [ Homo sapiens ]
Species	Human
Resistance	Hygromycin
Selection	Hygromycin
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) [ Homo sapiens ]
Gene Symbol	UPF1
Synonyms	HUPF1; NORF1; RENT1; smg-2; pNORF1
GeneID	5976
Uni ProtID	Q92900
mRNA Refseq	NM_002911.3
Protein Refseq	NP_002902.2
Chromosome Location	19p13.2-p13.11
Function	ATP binding; ATP-dependent RNA helicase activity; DNA binding; RNA binding; chromatin binding; helicase activity; protein binding; zinc ion binding;
Pathway	Exon junction complex (EJC), organism-specific biosystem; Gene Expression, organism-specific biosystem; Nonsense Mediated Decay Enhanced by the Exon Junction Complex, organism-specific biosystem; Nonsense Mediated Decay Independent of the Exon Junction Complex, organism-specific biosystem; Nonsense-Mediated Decay, organism-specific biosystem; RNA transport, organism-specific biosystem; RNA transport, conserved biosystem;
MIM	601430

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