Pages
Products

UPF1


Official Full Name
UPF1 RNA helicase and ATPase
Organism
Homo sapiens
Gene ID
5976
Background
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Synonyms
UTF; HUPF1; NORF1; RENT1; smg-2; pNORF1

Cat.No. Product Name Price
SHH440733 shRNA set against Human UPF1 (NM_002911.3) Inquiry
SHH440736 shRNA set against Mouse UPF1 (NM_030680.2) Inquiry
SHW018527 shRNA set against Danio rerio UPF1 (NM_213474) Inquiry
Cat.No. Product Name Price
CDCR262999 Mouse Upf1 ORF Clone(NM_030680.2) Inquiry
CDFH020878 Human UPF1 cDNA Clone(NM_002911.3) Inquiry
MiUTR1H-11025 UPF1 miRNA 3'UTR clone Inquiry
CDCB180002 Danio rerio UPF1 ORF Clone (NM_213474) Inquiry
CDCR237209 Mouse Upf1 ORF Clone(NM_001122829.1) Inquiry
CDCR284387 Human UPF1 ORF Clone(NM_002911.3) Inquiry
Quick Inquiry