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shRNA set against Human TLR2 (NM_003264.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH427960

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Gene Information

Cat. No. SHH427960
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr TLR2
Gene Name TLR2 toll-like receptor 2 [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name TLR2 toll-like receptor 2 [ Homo sapiens ]
Gene Symbol TLR2
Synonyms TIL4; CD282
Gene Description toll-like receptor 2
GeneID 7098
Uni ProtID B3KWR9
mRNA Refseq NM_003264.3
Protein Refseq NP_003255.2
Chromosome Location 4q32
Function Gram-positive bacterial cell surface binding; diacyl lipopeptide binding; lipopolysaccharide receptor activity; lipoteichoic acid binding; pattern recognition receptor activity; peptidoglycan binding; protein binding; protein heterodimerization activity; receptor activity; transmembrane signaling receptor activity; triacyl lipopeptide binding;
Pathway Activated TLR4 signalling, organism-specific biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Beta defensins, organism-specific biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Defensins, organism-specific biosystem;
MIM 603028
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