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shRNA set against Human PTTG1(NM_004219.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHR154464

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Gene Information

Cat. No. SHR154464
Description Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence. The sequences of 19~29mer shRNAi will be delivered with shRNA clones.
Gene Abbr PTTG1
Gene Name PTTG1 pituitary tumor-transforming 1 [ Homo sapiens ]
Species Human
Report Gene eGFP
Content Each set contains 4 shRNA expression constructs.
Promoter H1
Selection Marker Puromycin
Format 5 μg purified plasmid
Unit Size 5 μg
Gene Name PTTG1 pituitary tumor-transforming 1 [ Homo sapiens ]
Gene Symbol PTTG1
Synonyms EAP1; PTTG; HPTTG; TUTR1
Gene Description pituitary tumor-transforming 1
Gene ID 9232
Uni Prot ID O95997
m RNA Refseq NM_004219.2
Protein Refseq NP_004210.1
Chromosome Location 5q35.1
Function SH3 domain binding; cysteine-type endopeptidase inhibitor activity; heat shock protein binding; protein binding; ribosome binding; sequence-specific DNA binding transcription factor activity;
Pathway APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem;
MIM 604147
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