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Panoply™ Human PTTG1 Knockdown Stable Cell Line

Cat.No.
CSC-DC012738
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
PTTG1
Synonyms
EAP1; PTTG; HPTTG; TUTR1
Gene Description
pituitary tumor-transforming 1
Gene ID
UniProt ID
O95997
mRNA Refseq
Protein Refseq
Chromosome Location
5q35.1
Function
SH3 domain binding; cysteine-type endopeptidase inhibitor activity; heat shock protein binding; protein binding; ribosome binding; sequence-specific DNA binding transcription factor activity;
Pathway
APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem;
MIM

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