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shRNA set against Human PRF1(NM_001083116.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHR138810

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Gene Information

Cat. No. SHR138810
Description Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence. The sequences of 19~29mer shRNAi will be delivered with shRNA clones.
Gene Abbr PRF1
Gene Name PRF1 perforin 1 (pore forming protein) [ Homo sapiens ]
Species Human
Report Gene eGFP
Content Each set contains 4 shRNA expression constructs.
Promoter H1
Selection Marker Puromycin
Format 5 μg purified plasmid
Unit Size 5 μg
Gene Name PRF1 perforin 1 (pore forming protein) [ Homo sapiens ]
Gene Symbol PRF1
Synonyms P1; PFP; FLH2; PFN1; HPLH2
Gene Description perforin 1 (pore forming protein)
Gene ID 5551
Uni Prot ID P14222
m RNA Refseq NM_005041.4
Protein Refseq NP_005032.2
Chromosome Location 10q22
Function calcium ion binding; protein binding; wide pore channel activity;
Pathway Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Apoptosis, organism-specific biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; Caspase cascade in apoptosis, organism-specific biosystem; Downstream signaling in naive CD8+ T cells, organism-specific biosystem;
MIM 170280
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