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PRF1


Official Full Name
perforin 1
Organism
Homo sapiens
Gene ID
5551
Background
This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]
Synonyms
P1; PFP; HPLH2

Cat.No. Product Name Price
SHR138810 shRNA set against Human PRF1(NM_001083116.1) Inquiry
SHH382468 shRNA set against Human PRF1 (NM_005041.4) Inquiry
SHH382472 shRNA set against Mouse PRF1 (NM_011073.3) Inquiry
SHH382479 shRNA set against Rat PRF1 (NM_017330.2) Inquiry
SHH453832 shRNA set against Human ZNF395 (NM_018660.2) Inquiry
SHR138774 shRNA set against Human PRF1(NM_005041.4) Inquiry
SHR138828 shRNA set against Rat Prf1(NM_017330.2) Inquiry
SHW016346 shRNA set against Danio rerio ZNF395 (NM_200108) Inquiry
Cat.No. Product Name Price
CDCR378430 Rat Prf1 ORF Clone(NM_017330.2) Inquiry
MiUTR1H-08247 PRF1 miRNA 3'UTR clone Inquiry
MiUTR1H-08246 PRF1 miRNA 3'UTR clone Inquiry
CDFR011044 Rat Prf1 cDNA Clone(NM_017330.2) Inquiry
CDFH015066 Human PRF1 cDNA Clone(NM_001083116.1) Inquiry
CDFG001976 Human ZNF395 cDNA Clone(NM_018660.2) Inquiry
MiUTR1H-11586 ZNF395 miRNA 3'UTR clone Inquiry
MiUTR1R-06040 PRF1 miRNA 3'UTR clone Inquiry
CDCR303990 Human ZNF395 ORF Clone(NM_018660.2) Inquiry
CDCS407344 Human PRF1 ORF Clone (BC063043) Inquiry
CDCR250057 Mouse Prf1 ORF Clone(NM_011073.3) Inquiry
CDCL149598 Human PRF1 ORF clone (NM_005041.4) Inquiry
CDCB192254 Rabbit PRF1 ORF clone (XM_008270008.1) Inquiry
CDCB188330 Rabbit ZNF395 ORF clone (XM_008249141.1) Inquiry
CDCB177821 Danio rerio ZNF395 ORF Clone (NM_200108) Inquiry
CDCR345926 Human PRF1 ORF Clone(NM_001083116.1) Inquiry
CDCB157807 Human PRF1 ORF clone (BC063043) Inquiry
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