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shRNA set against Human P4HB (NM_000918.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH369676

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Gene Information

Cat. No. SHH369676
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr P4HB
Gene Name P4HB prolyl 4-hydroxylase, beta polypeptide [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name P4HB prolyl 4-hydroxylase, beta polypeptide [ Homo sapiens ]
Gene Symbol P4HB
Synonyms DSI; GIT; PDI; PHDB; PDIA1; PO4DB; PO4HB; PROHB; ERBA2L; P4Hbeta
Gene Description procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide
GeneID 5034
Uni ProtID P07237
mRNA Refseq NM_000918.3
Protein Refseq NP_000909.2
Chromosome Location 17q25
Function electron carrier activity; procollagen-proline 4-dioxygenase activity; protein binding; protein disulfide isomerase activity; protein disulfide oxidoreductase activity; protein heterodimerization activity;
Pathway Chylomicron-mediated lipid transport, organism-specific biosystem; Collagen biosynthesis and modifying enzymes, organism-specific biosystem; Collagen formation, organism-specific biosystem; Extracellular matrix organization, organism-specific biosystem; Lipid digestion, mobilization, and transport, organism-specific biosystem; Lipoprotein metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem;
MIM 176790
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