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shRNA set against Human FTO (NM_001080432.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH297549

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Gene Information

Cat. No. SHH297549
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr FTO
Gene Name FTO fat mass and obesity associated [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name FTO fat mass and obesity associated [ Homo sapiens ]
Gene Symbol FTO
Synonyms FTO; fat mass and obesity associated; alpha-ketoglutarate-dependent dioxygenase FTO; KIAA1752; MGC5149; protein fto; fat mass and obesity-associated protein;
GeneID 79068
Uni ProtID Q9C0B1
mRNA Refseq BC003583
Chromosome Location 16q12.2
Function DNA-N1-methyladenine dioxygenase activity; ferrous iron binding; metal ion binding; oxidative DNA demethylase activity; oxidative RNA demethylase activity; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;
MIM 610966
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