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FTO

Official Full Name
FTO alpha-ketoglutarate dependent dioxygenase
Organism
Homo sapiens
GeneID
79068
Background
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]
Synonyms
GDFD; IFEX9; ALKBH9; BMIQ14;

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