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Rat Fto ORF Clone(NM_001039713.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR371769

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Product Information

Gene Information

Cat. No. CDCR371769
Product Type ORF Clone
Gene Abbr Fto
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1509 bp
Vector pCMV6-Entry
Target Gene FTO
Background This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]
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