shRNA set against Human FBXW7 (NM_033632.3)

Name: shRNA set against Human FBXW7 (NM_033632.3)
SKU: SHH293569
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH293569

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Product Information

Gene Information

Cat. No.	SHH293569
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	FBXW7
Gene Name	FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase [ Homo sapiens ]
Gene Symbol	FBXW7
Synonyms	AGO; CDC4; FBW6; FBW7; hAgo; FBX30; FBXW6; SEL10; hCdc4; FBXO30; SEL-10
Gene Description	F-box and WD repeat domain containing 7
GeneID	55294
Uni ProtID	Q969H0
mRNA Refseq	NM_001013415.1
Protein Refseq	NP_001013433.1
Chromosome Location	4q31.3
Function	protein binding; sequence-specific DNA binding transcription factor activity;
Pathway	Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Association of TriC/CCT with target proteins during biosynthesis, organism-specific biosystem; Chaperonin-mediated protein folding, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem;
MIM	606278

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