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Human FBXW7 ORF clone (NM_018315.4)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCL107521

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Product Information

Gene Information

Cat. No. CDCL107521
Description Homo sapiens F-box and WD repeat domain containing 7 (FBXW7), transcript variant 2, mRNA.
Product Type ORF clone
Gene Abbr FBXW7
Gene Name FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase [ Homo sapiens ]
Species Human
ORF Size 1884bp
Format purified plasmid
Vector pDONR
Warning Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.
Gene Name FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase [ Homo sapiens ]
Gene Symbol FBXW7
Synonyms AGO; CDC4; FBW6; FBW7; hAgo; FBX30; FBXW6; SEL10; hCdc4; FBXO30; SEL-10
Gene Description F-box and WD repeat domain containing 7
GeneID 55294
Uni ProtID Q969H0
mRNA Refseq NM_001013415.1
Protein Refseq NP_001013433.1
Chromosome Location 4q31.3
Function protein binding; sequence-specific DNA binding transcription factor activity;
Pathway Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Association of TriC/CCT with target proteins during biosynthesis, organism-specific biosystem; Chaperonin-mediated protein folding, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem;
MIM 606278
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