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shRNA set against Human ERCC5 (NM_000123.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH286925

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Gene Information

Cat. No. SHH286925
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr ERCC5
Gene Name ERCC5 excision repair cross-complementing rodent repair deficiency, complementation group 5 [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name ERCC5 excision repair cross-complementing rodent repair deficiency, complementation group 5 [ Homo sapiens ]
Gene Symbol ERCC5
Synonyms ERCC5; excision repair cross-complementing rodent repair deficiency, complementation group 5; ERCM2, xeroderma pigmentosum, complementation group G , XPGC; DNA repair protein complementing XP-G cells; Cockayne syndrome; XPG-complementing protein; DNA excision repair protein ERCC-5; xeroderma pigmentosum, complementation group G; XPG; UVDR; XPGC; COFS3; ERCM2;
Gene ID 2073
Uni Prot ID P28715
m RNA Refseq BC031522
Chromosome Location 13q22-q34
Function DNA binding; bubble DNA binding; double-stranded DNA binding; endodeoxyribonuclease activity; endonuclease activity; endonuclease activity; metal ion binding; protein N-terminus binding; protein binding; protein homodimerization activity; single-stranded DNA binding; single-stranded DNA binding;
Pathway DNA Repair, organism-specific biosystem; Dual incision reaction in GG-NER, organism-specific biosystem; Dual incision reaction in TC-NER, organism-specific biosystem; Formation of incision complex in GG-NER, organism-specific biosystem; Formation of transcription-coupled NER (TC-NER) repair complex, organism-specific biosystem; Global Genomic NER (GG-NER), organism-specific biosystem; Nucleotide Excision Repair, organism-specific biosystem;
MIM 133530
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