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ERCC5


Official Full Name
ERCC excision repair 5, endonuclease
Organism
Homo sapiens
Gene ID
2073
Background
This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, cognitive disability, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene. [provided by RefSeq, Feb 2011]
Synonyms
XPG; UVDR; XPGC; COFS3; ERCM2; ERCC5-201

Cat.No. Product Name Price
SHH286925 shRNA set against Human ERCC5 (NM_000123.3) Inquiry
SHH286929 shRNA set against Mouse ERCC5 (NM_011729.2) Inquiry
SHH286933 shRNA set against Rat ERCC5 (NM_001106910.1) Inquiry
SHW002223 shRNA set against Chicken ERCC5 (NM_001034823) Inquiry
Cat.No. Product Name Price
CDCS405438 Human ERCC5 ORF Clone (BC031522) Inquiry
CDFR006636 Rat Ercc5 cDNA Clone(NM_001106910.1) Inquiry
MiUTR1H-03291 ERCC5 miRNA 3'UTR clone Inquiry
CDCB163698 Chicken ERCC5 ORF Clone (NM_001034823) Inquiry
CDCR061106 Mouse Ercc5 ORF clone (NM_011729.2) Inquiry
CDCR373687 Rat Ercc5 ORF Clone(NM_001106910.1) Inquiry
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