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shRNA set against Human DNMT3B (NM_006892.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH280025

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Gene Information

Cat. No. SHH280025
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr DNMT3B
Gene Name DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta [ Homo sapiens ]
Gene Symbol DNMT3B
Synonyms ICF; ICF1; M.HsaIIIB
Gene Description DNA (cytosine-5-)-methyltransferase 3 beta
GeneID 1789
Uni ProtID Q9UBC3
mRNA Refseq NM_175848.1
Protein Refseq NP_787044.1
Chromosome Location 20q11.2
Function DNA (cytosine-5-)-methyltransferase activity; DNA (cytosine-5-)-methyltransferase activity; DNA (cytosine-5-)-methyltransferase activity; DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates; DNA-methyltransferase activity; metal ion binding; protein binding; transcription corepressor activity; transcription corepressor activity; unmethylated CpG binding;
Pathway Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Methionine degradation, organism-specific biosystem; Methionine degradation, conserved biosystem; One Carbon Metabolism, organism-specific biosystem;
MIM 602900
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