Pages
Products

Mouse Dnmt3b cDNA Clone(NM_001003963.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG016246

Inquire for Price

Product Information

Gene Information

Cat. No. CDFG016246
Product Type cDNA clone
Gene Abbr Dnmt3b
Species Mouse
ORF Size 2391bp
Size 10 ug
Vector pCMV6Entry
Target Gene DNMT3B
Background CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011]
Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Needs improvement

Satisfaction

General satisfaction

Very satisfaction