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shRNA set against Human DNMT3A (NM_022552.4)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH280017

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Gene Information

Cat. No. SHH280017
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr DNMT3A
Gene Name DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha [ Homo sapiens ]
Gene Symbol DNMT3A
Synonyms DNMT3A2; M.HsaIIIA
Gene Description DNA (cytosine-5-)-methyltransferase 3 alpha
GeneID 1788
Uni ProtID Q9Y6K1
mRNA Refseq NM_175630.1
Protein Refseq NP_783329.1
Chromosome Location 2p23
Function DNA (cytosine-5-)-methyltransferase activity; DNA binding; chromatin binding; metal ion binding; protein binding;
Pathway Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Methionine degradation, organism-specific biosystem; Methionine degradation, conserved biosystem; One Carbon Metabolism, organism-specific biosystem; Validated targets of C-MYC transcriptional repression, organism-specific biosystem;
MIM 602769
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