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DNMT3A

Official Full Name
DNA methyltransferase 3 alpha
Organism
Homo sapiens
GeneID
1788
Background
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016]
Synonyms
TBRS; HESJAS; DNMT3A2; M.HsaIIIA;

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