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shRNA set against Human DNMT1 (NM_001379.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH280005

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Gene Information

Cat. No. SHH280005
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr DNMT1
Gene Name DNMT1 DNA (cytosine-5-)-methyltransferase 1 [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name DNMT1 DNA (cytosine-5-)-methyltransferase 1 [ Homo sapiens ]
Gene Symbol DNMT1
Synonyms AIM; DNMT; MCMT; CXXC9; HSN1E
Gene Description DNA (cytosine-5-)-methyltransferase 1
GeneID 1786
Uni ProtID I6L9H2
mRNA Refseq NM_001130823.1
Protein Refseq NP_001124295.1
Chromosome Location 19p13.2
Function DNA (cytosine-5-)-methyltransferase activity; DNA binding; DNA-methyltransferase activity; RNA binding; methyl-CpG binding; protein binding; transcription factor binding; zinc ion binding;
Pathway Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Methionine degradation, organism-specific biosystem; Methionine degradation, conserved biosystem; One Carbon Metabolism, organism-specific biosystem; Regulation of retinoblastoma protein, organism-specific biosystem;
MIM 126375
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