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shRNA set against Human CAD (NM_004341.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH253573

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Gene Information

Cat. No. SHH253573
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr CAD
Gene Name CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase [ Homo sapiens ]
Gene Symbol CAD
Gene Description carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
GeneID 790
Uni ProtID P27708
mRNA Refseq NM_004341.3
Protein Refseq NP_004332.2
Chromosome Location 2p22-p21
Function ATP binding; aspartate binding; aspartate carbamoyltransferase activity; aspartate carbamoyltransferase activity; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; dihydroorotase activity; dihydroorotase activity; enzyme binding; identical protein binding; metal ion binding; protein kinase activity;
Pathway Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Endothelin, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Pyrimidine biosynthesis, organism-specific biosystem; Pyrimidine metabolism, organism-specific biosystem;
MIM 114010
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