Recombinant Rhesus Macaque CD160 (C-6His)

Name: Recombinant Rhesus Macaque CD160 (C-6His)
SKU: RP00305
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00305 Tag : C-6His

Expressed Region : Met1-Leu158 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00305
Description	The Recombinant Rhesus Macaque CD160 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Met1-Leu158 with a 6His tag at the C terminus.
Species	Rhesus Macaque
Tag	C-6His
Mol Weight	15.9 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Met1-Leu158
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	CD160
Synonyms	CD160 antigen; CD160

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CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.

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