Transfected Stable Cell Lines
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Cat. No. : RP00578 Tag : C-Fc
Expressed Region : Tyr19-Phe495 Expression System : Human Cell
| Cat. No. | RP00578 |
| Description | Recombinant Rhesus Macaque ANGPT2 (C-Fc) is produced in our Human Cell expression system. The amino acid region expressed is Tyr19-Phe495 with a Fc tag at the C terminus. |
| Species | Rhesus Macaque |
| Tag | C-Fc |
| Mol Weight | 81.7 KDa |
| Conjugate | Unconjugated |
| Format | Powder |
| Expressed Region | Tyr19-Phe495 |
| Expression System | Human Cell |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Purity |
>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS. |
| Endotoxin Level | < 1 EU/µg of protein by LAL method |
| Storage | Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles. |
| Shipping | The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below. |
| Reconstitution | Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Target Gene | ANGPT2 |
| Background | This gene belongs to the angiopoietin family of growth factors. The protein encoded by this gene is an antagonist of angiopoietin 1, and both angiopoietin 1 and angiopoietin 2 are ligands for the endothelial TEK receptor tyrosine kinase. Angiopoietin 2 is upregulated in multiple inflammatory diseases and is implicated in the direct control of inflammation-related signaling pathways. The encoded protein affects angiogenesis during embryogenesis and tumorigenesis, disrupts the vascular remodeling ability of angiopoietin 1, and may induce endothelial cell apoptosis. This gene serves a prognostic biomarker for acute respiratory distress syndrome. |
| Synonyms | AGPT2; ANG2; ANG-2; angiopoietin 2; Angiopoietin-2; angiopoietin-2a; angiopoietin-2B; angiopoitin 2; ANGPT2; Tie2-ligand |
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