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Recombinant Human ANGPT2 (C-6His)

For research use only. Not intended for any clinical use.

Cat. No. :   RP00544 Tag :   C-6His

Expressed Region :   Lys275-Phe496 Expression System :   Human Cell

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Product Information

Gene Information

Cat. No. RP00544
Description Recombinant Human ANGPT2 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Lys275-Phe496 with a 6His tag at the C terminus.
Species Human
Tag C-6His
Mol Weight 23.6 KDa
Conjugate Unconjugated
Format Powder
Expressed Region Lys275-Phe496
Expression System Human Cell
Formulation Lyophilized from a 0.2 μm filtered solution of 20 mM MOPS, 150 mM NaCl, 0.1% CHAPS, pH 7.5.
Purity >95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
Endotoxin Level < 1 EU/µg of protein by LAL method
Storage Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Target Gene ANGPT2
Background This gene belongs to the angiopoietin family of growth factors. The protein encoded by this gene is an antagonist of angiopoietin 1, and both angiopoietin 1 and angiopoietin 2 are ligands for the endothelial TEK receptor tyrosine kinase. Angiopoietin 2 is upregulated in multiple inflammatory diseases and is implicated in the direct control of inflammation-related signaling pathways. The encoded protein affects angiogenesis during embryogenesis and tumorigenesis, disrupts the vascular remodeling ability of angiopoietin 1, and may induce endothelial cell apoptosis. This gene serves a prognostic biomarker for acute respiratory distress syndrome.
Synonyms AGPT2; ANG2; ANG-2; angiopoietin 2; Angiopoietin-2; angiopoietin-2a; angiopoietin-2B; angiopoitin 2; ANGPT2; Tie2-ligand
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