Recombinant Rat CD86 (C-6His)

Name: Recombinant Rat CD86 (C-6His)
SKU: RP00204
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00204 Tag : C-6His

Expressed Region : Vla29-Lys247 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00204
Description	The Recombinant Rat CD86 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Vla29-Lys247 with a 6His tag at the C terminus.
Species	Rat
Tag	C-6His
Mol Weight	25.9 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Vla29-Lys247
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	Cd86
Background	This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
Synonyms	T-lymphocyte activation antigen CD86; Activation B7-2 antigen; CD86

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