Recombinant Rat CD86 (C-6His)

Name: Recombinant Rat CD86 (C-6His)
SKU: RP00204

Cat.No. : RP00204 Tag: C-6His

Expressed Region: Vla29-Lys247 Expression System: Human Cell

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Product Details

Target Information

Cat. No.	RP00204
Description	The Recombinant Rat CD86 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Vla29-Lys247 with a 6His tag at the C terminus.
Species	Rat
Tag	C-6His
Mol. Weight	25.9 KDa
Expressed Region	Vla29-Lys247
Expression System	Human Cell
Format	Powder
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Conjugate	Unconjugated
Endotoxin Level	< 1 EU/µg of protein by LAL method
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	Cd86
Background	This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
Synonyms	T-lymphocyte activation antigen CD86; Activation B7-2 antigen; CD86

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