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Humanized CD86 Murine Tumor Cell Line

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-RH0116M

Host Cell :   CT26 Size :   >1x106 frozen cells/vial

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Cell Line Information

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Gene Information

Cat. No. CSC-RH0116M
Description This transgenic cell line carries humanized CD86. The endogenous mouse Cd86 gene was replaced by human CD86 gene.
Target Gene CD86
Alias B7-2, B7.2, B70, CD28LG2, LAB72
Host Cell CT26
Host Cell Species Mus musculus (Mouse)
Size >1x106 frozen cells/vial
Storage Liquid nitrogen
Shipping Dry ice
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name CD86 CD86 molecule [ Homo sapiens ]
Gene Symbol CD86
Synonyms CD86; CD86 molecule; CD28LG2, CD86 antigen (CD28 antigen ligand 2, B7 2 antigen); T-lymphocyte activation antigen CD86; B lymphocyte antigen B7 2; B7 2; B7.2; BU63; FUN-1; CTLA-4 counter-receptor B7.2; B-lymphocyte activation antigen B7-2; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); B70; B7-2; LAB72; CD28LG2; MGC34413;
Gene ID 942
Uni Prot ID P42081
m RNA Refseq BC040261
Chromosome Location 3q21
Function coreceptor activity; protein binding; receptor activity;
Pathway Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent PI3K/Akt signaling, organism-specific biosystem;
MIM 601020
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