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Cat. No. : RP00166 Tag : C-6His
Expressed Region : Ala2-Ala686 Expression System : Human Cell
| Cat. No. | RP00166 |
| Description | The Recombinant Mouse TGM2 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Ala2-Ala686 with a 6His tag at the C terminus. |
| Species | Mouse |
| Tag | C-6His |
| Mol Weight | 78 KDa |
| Conjugate | Unconjugated |
| Format | Liquid |
| Expressed Region | Ala2-Ala686 |
| Expression System | Human Cell |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, pH 7.5. |
| Purity |
>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS. |
| Endotoxin Level | < 1 EU/µg of protein by LAL method |
| Storage | Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles. |
| Shipping | The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below. |
| Target Gene | Tgm2 |
| Background | Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. |
| Synonyms | Protein-glutamine gamma-glutamyltransferase 2; Tgm2; Tissue transglutaminase; Transglutaminase C; TGase-2 |
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