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Panoply™ Human TGM2 Knockdown Stable Cell Line

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-DC015876

Host Cell :   HEK293 (Hela and other cell types are also available) Validation :   Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No. CSC-DC015876
Description Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene TGM2
Host Cell HEK293 (Hela and other cell types are also available)
Host Cell Species Homo sapiens (Human)
Applications

(1) Studying gene functions

(2) Studying gene interactions and signaling pathways

(3) Target validation and drug discovery

(4) Designing diseases models

Size >1 × 106 cells / vial
Stability Validated for at least 10 passages
Validation Real-Time RCR
Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Storage Liquid Nitrogen
Shipping Dry Ice
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) [ Homo sapiens ]
Gene Symbol TGM2
Synonyms TG2; TGC; GNAH; G-ALPHA-h
Gene Description transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
Gene ID 7052
Uni Prot ID P21980
m RNA Refseq NM_004613.2
Protein Refseq NP_004604.2
Chromosome Location 20q12
Function GTP binding; metal ion binding; protein binding; protein domain specific binding; protein-glutamine gamma-glutamyltransferase activity;
Pathway Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem; Thromboxane A2 receptor signaling, organism-specific biosystem;
MIM 190196
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