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Cat. No. : RP00310 Tag : C-6His
Expressed Region : Thr25-Ser232 Expression System : Human Cell
| Cat. No. | RP00310 |
| Description | The Recombinant Mouse FOLR1 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Thr25-Ser232 with a 6His tag at the C terminus. |
| Species | Mouse |
| Tag | C-6His |
| Mol Weight | 25.3 KDa |
| Conjugate | Unconjugated |
| Format | Powder |
| Expressed Region | Thr25-Ser232 |
| Expression System | Human Cell |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Purity |
>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS. |
| Endotoxin Level | < 1 EU/µg of protein by LAL method |
| Storage | Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles. |
| Shipping | The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below. |
| Reconstitution | Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Target Gene | Folr1 |
| Background | The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. |
| Synonyms | Adult folate-binding protein; FBP; folate binding protein; folate receptor 1 (adult); Folate receptor 1; folate receptor alpha; Folate receptor, adult; Folbp1; FOLR; FOLR1; FR-alpha; KB cells FBP; MOv18; Ovarian tumor-associated antigen MOv18 |
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