Recombinant Mouse CD74 (C-6His)

Name: Recombinant Mouse CD74 (C-6His)
SKU: RP00246
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00246 Tag : C-6His

Expressed Region : Gln56-Leu215 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00246
Description	The Recombinant Mouse CD74 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Gln56-Leu215 with a 6His tag at the C terminus.
Species	Mouse
Tag	C-6His
Mol Weight	19.4 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Gln56-Leu215
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	Cd74
Background	The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms	Cluster of Differentiation 74;CD74 antigen; CD74 molecule, major histocompatibility complex, class II invariant chain; DHLAG gamma chain of class II antigens; HLA class II histocompatibility antigen gamma chain; HLADG; HLA-DR antigens-associated invariant chain; HLA-DR-gamma; Ia antigen-associated invariant chain; Ia-associated invariant chain; Ia-GAMMA; MHC HLA-DR gamma chain; CD74; DHLAG; HLADG; Ia-gamma; INVG34;

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