Recombinant Human TNFSF13 (N-Flag-His)

Name: Recombinant Human TNFSF13 (N-Flag-His)
SKU: RP00550
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00550 Tag : N-Flag-His

Expressed Region : Lys112-Leu250 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00550
Description	Recombinant Human TNFSF13 (N-Flag-His) is produced in our Human Cell expression system. The amino acid region expressed is Lys112-Leu250 with a Flag-His tag at the N terminus.
Species	Human
Tag	N-Flag-His
Mol Weight	50 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Lys112-Leu250
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 1M NaCl, pH8.3.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	TNFSF13
Synonyms	Tumor necrosis factor ligand superfamily member 13; A proliferation-inducing ligand; APRIL; TNF- and APOL-related leukocyte expressed ligand 2; TALL-2; TNF-related death ligand 1; TRDL-1; CD256; TNFSF13

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The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.

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