Recombinant Human Tie-2 (C-Fc)

Name: Recombinant Human Tie-2 (C-Fc)
SKU: RP00404
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00404 Tag : C-Fc

Expressed Region : Ala23-Lys745 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00404
Description	The Recombinant Human Tie-2 (C-Fc) is produced in our Human Cell expression system. The amino acid region expressed is Ala23-Lys745 with a Fc tag at the C terminus.
Species	Human
Tag	C-Fc
Mol Weight	107.4 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Ala23-Lys745
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	Tie2
Background	This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Synonyms	angiopoietin-1 receptor; CD202b antigen; CD202b; EC 2.7.10; EC 2.7.10.1; hTIE2; p140 TEK; soluble TIE2 variant 1; soluble TIE2 variant 2; TEK tyrosine kinase, endothelial; TEK; Tie2; Tie-2; VMCM; VMCM1

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